Physician Formulated SQF Certified 503A Compounded

DSIP · Nighttime Relaxation Spray

Reclaim your nights.Sleep like you used to.

You've been lying awake — searching for something that actually works, without the grogginess or dependency.

  • Fall asleep easier — a calmer mind at bedtime
  • Deeper, more restorative sleep through the night
  • Wake up clear — no morning grogginess
  • No sedatives. No dependency. No rebound.
Dr. Amy Seinfeld, D.O.
Physician-formulated by Dr. Amy Seinfeld, D.O.
Formulation Authority · Ginspire Health LLC
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Ships Cold
FDA-Registered Facility
SQF Certified
100% American Owned 100% Tested for Purity Lab Certified & Verified 98% Customer Satisfaction Guaranteed Delivery

Drift into deep, restorative sleep with a peptide designed to calm the mind and relax the body. DSIP (Delta Sleep-Inducing Peptide) naturally supports your sleep cycle, helping reduce stress and improve sleep quality without morning grogginess. Experience a smoother transition into rest, deeper recovery overnight, and a refreshed, balanced state when you wake.

Physician-formulated by Dr. Amy Seinfeld, D.O.
Prepared in a licensed SQF-certified, FDA-registered compounding facility
No fillers, preservatives, or parabens
Compounded to 503A pharmaceutical standards -- no reconstitution required
Ships cold -- pre-mixed and ready to use

Available with a valid consultation. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Regular price $99.99 Sale price$129.99
DSIP Nighttime Relaxation Spray
$99.99$129.99

DSIP Nasal Spray

Everything You Need to Know

DSIP — Delta Sleep-Inducing Peptide — is a naturally occurring compound that promotes deep, restorative sleep without sedation or dependency. It works with your body's own rhythms rather than overriding them.

  • Promotes Deep, Restorative Sleep — supports healthy slow-wave sleep so you wake rested.
  • Reduces Stress & Anxiety — lowers cortisol and supports a calm nervous system response.
  • Supports Hormone Balance — may help normalize stress-related hormone activity.
  • Enhances Recovery — promotes muscle and tissue repair during rest.
  • Improves Mood & Focus — supports daytime alertness through better-quality sleep.
  • Neuroprotective Effects — reduces oxidative stress and supports cognitive resilience.

DSIP is ideal for anyone experiencing poor sleep quality, difficulty falling asleep, stress-related insomnia, or disrupted sleep cycles — particularly those who want to improve sleep naturally, without melatonin, sedatives, or habit-forming sleep aids.

Melatonin signals your body that it's dark outside. Sedatives suppress your nervous system. DSIP does neither — it works at a deeper level by reducing cortisol, supporting the HPA axis, and enhancing the quality of slow-wave sleep your body already produces. No rebound insomnia. No next-day grogginess. No dependency.

Yes. DrSeinfeld.com DSIP Nasal Spray is non-steroidal and contains no toxic fillers or preservatives. Each batch is micro-filtered in our SQF-certified, FDA-registered compounding facility under the oversight of Dr. Amy Seinfeld, D.O. — formulated for consistent purity and potency.

Administer 1 spray into each nostril approximately 30 to 60 minutes before bedtime. Lay down immediately after administration to enhance absorption. May be used up to twice nightly — max 4 total sprays per 24-hour period. Use consistently for best results.

DSIP nasal spray is generally well tolerated. Mild side effects may include temporary nasal irritation or dryness, mild drowsiness if taken too early in the evening, vivid dreams during the first few nights, or rarely a mild headache. These effects are typically short-lived and resolve without intervention.

Administration Protocol

Dosage
1 spray per nostril at night. Up to twice nightly — max 4 sprays per 24 hours.
Timing
30–60 minutes before bedtime. Lay down immediately after administration to enhance absorption.
Frequency
Use daily as directed. Do not exceed 4 total sprays in a 24-hour period.
Duration
Use nightly. Consistent use produces the best long-term results for sleep regulation.
Storage & Handling
• Store in the refrigerator. Do not freeze.
• Protect from light and heat.
• Keep out of reach of children.
Ensure nasal passages are clear before spraying to maximize absorption.

* These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

The Experience

What to Expect, Night by Night

DSIP builds with consistent use. Here's the typical progression patients describe.

Nights 1-3: calm bedtime
Nights 1–3
Easier Wind-Down
A calmer transition to sleep within the first few nights. Many notice they fall asleep more easily and the mind feels quieter at bedtime.
Weeks 1-2: deep, restful sleep
Weeks 1–2
Deeper, Steadier Sleep
Sleep feels deeper and less interrupted. Mornings start to feel clearer — rested rather than groggy — and daytime mood feels more stable.
Weeks 4-8: energized, rested morning
Weeks 4–8
Full Circadian Reset
With nightly use, your sleep-wake rhythm recalibrates. Sustained deep sleep, improved recovery, and steady daytime energy build over the full protocol.

Individual results may vary. These statements have not been evaluated by the FDA.

DSIP vs melatonin

The Comparison

DSIP vs. Melatonin

Melatonin doesn't actually make you sleep — it's a signal. It tells your brain the sun has gone down and nudges your internal clock. That can help when your timing is off, like jet lag or shift work, but it does nothing for the stress and cortisol that keep most people staring at the ceiling. And because a typical dose floods your system with far more melatonin than your body would ever produce on its own, many people wake up groggy, foggy, or with strange, vivid dreams.

DSIP works further upstream. Instead of overriding your clock, it helps lower cortisol and support the HPA axis so your nervous system can finally downshift — then enhances the deep, slow-wave sleep your body already produces. Patients describe it as less "knocked out" and more "finally able to fall and stay asleep," without the next-day hangover or the tolerance that tends to build with nightly melatonin.

Is DSIP stronger than melatonin?
They work differently. Melatonin shifts your sleep timing; DSIP supports the depth and quality of sleep by calming the stress response — which is why people who feel "immune" to melatonin often notice DSIP.
Will DSIP make me groggy like melatonin can?
It's formulated to avoid the morning fog. DSIP enhances natural slow-wave sleep rather than sedating you, so most users report waking clearer, not heavier.
Can I take DSIP instead of melatonin?
Many customers switch from melatonin to DSIP. If you take prescription medication or have a medical condition, check with your provider first.

* These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

What It Does

Six Reasons Clinicians Recommend DSIP

Delta Sleep-Inducing Peptide works with your body's own rhythms to promote deep, restorative sleep without sedation or dependency.

Six reasons clinicians recommend DSIP

Promotes Deep, Restorative Sleep

Enhances deep, restorative sleep and supports healthy circadian rhythm regulation — so you wake up actually rested, not just having logged hours in bed.

Slow-Wave | Circadian | Rest

Reduces Stress & Anxiety

Lowers cortisol levels and supports a calm nervous system response — helping your body and mind transition into a restful state naturally, without sedatives or dependency.

Cortisol | Calm | Nervous System

Supports Hormone Balance

May help normalize stress-related hormone activity, including cortisol and growth hormone regulation — supporting overall endocrine balance during sleep cycles.

Hormones | Cortisol | Balance

Enhances Recovery

Promotes muscle and tissue repair during rest — making DSIP particularly valuable for active individuals, athletes, and anyone who needs their body to recover effectively overnight.

Muscle Repair | Tissue | Recovery

Improves Mood & Focus

Supports daytime alertness and mental clarity through better-quality sleep — because when your nights improve, your days follow. Patients report sharper focus and steadier mood after consistent use.

Alertness | Mood | Clarity

Neuroprotective Effects

Reduces oxidative stress and supports cognitive resilience — protecting neuronal health during the critical repair and consolidation processes that occur during deep sleep.

Neuroprotection | Resilience
Non-steroidal formula
No fillers or preservatives
SQF Certified facility
Formulated by Dr. Amy Seinfeld, D.O.

The Science

How DSIP Works Inside Your Body

Unlike melatonin or sedatives that force sleep, DSIP works with your body's natural sleep-wake architecture — enhancing the quality and depth of sleep you're already capable of.

01
Nasal Administration — 30–60 Minutes Before Bed

Administer 1 spray into each nostril 30–60 minutes before bedtime. The nasal mucosa absorbs DSIP rapidly — bypassing the digestive system and entering the bloodstream without first-pass metabolism. Lay down immediately to maximize absorption.

Bypasses digestion — faster onset than oral sleep aids
02
Cortisol Reduction & Nervous System Calming

Once absorbed, DSIP helps lower cortisol — the primary stress hormone that keeps the nervous system activated. By modulating the HPA axis, DSIP supports the physiological transition needed to enter and sustain deep sleep stages.

Cortisol reduction — nervous system regulation
03
Deep Sleep Stage Enhancement

DSIP promotes deeper slow-wave sleep — the stage where physical recovery, hormone regulation, and memory consolidation occur. Unlike sedatives that suppress sleep architecture, DSIP enhances its natural depth without blunting REM cycles.

Slow-wave sleep — no REM suppression
04
Cumulative Sleep Regulation

With consistent nightly use over 4–8 weeks, DSIP helps recalibrate your circadian rhythm and sleep-wake cycle. Most notice improvements within the first few nights, with deeper sleep and better daytime function building over the full protocol.

Full circadian recalibration at 4–8 weeks
How DSIP works
~Minutes
To initial absorption via nasal mucosa
First Few Nights
When most notice initial sleep improvements
4–8 Weeks
Recommended duration for full circadian regulation
Zero Dependency
No sedation, no habit formation, no rebound insomnia
DSIP vs sleep gummies

The Comparison

DSIP vs. Sleep Gummies

Most "sleep gummies" are just melatonin in candy form — usually 5 to 10mg, plus sugar, syrups, gelatin, and coloring. Beyond the additives, the format itself works against you: anything you chew and swallow has to survive your stomach and liver (first-pass metabolism) before a fraction of it reaches your bloodstream. That means a slower, blunted, less predictable effect — and a dessert right before bed.

DSIP skips all of that. Delivered as a nasal spray, it's absorbed directly through the nasal mucosa into the bloodstream — faster onset, no sugar, no fillers, no chewing. You're getting a precisely dosed peptide prepared in a licensed compounding pharmacy, not a confection engineered to taste good.

Are sleep gummies bad for you?
Not necessarily — but most are melatonin plus added sugar and fillers, often at a higher dose than you need. DSIP contains no sugar or fillers and uses a different mechanism entirely.
Why a nasal spray instead of a gummy?
Nasal delivery bypasses digestion, so absorption is faster and more complete than a gummy that must pass through the gut and liver first.
Do gummies and DSIP do the same thing?
No. Most gummies rely on melatonin to signal bedtime. DSIP supports deeper sleep by calming the stress response and enhancing slow-wave sleep.

* These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Why DrSeinfeld.com

Not All Peptide Brands Are Equal

Most peptide suppliers prioritize volume over patients. DrSeinfeld.com was built differently — by a physician, for real clinical outcomes.

Compounding facility and lab testing
DrSeinfeld.com
Our Standard
Other Peptide
Brands
Physician-supervised formulation by Dr. Amy Seinfeld, D.O.
Pre-mixed nasal spray — no reconstitution required
SQF Certified & FDA Registered compounding facility
Third-party purity tested — every batch
Pharmaceutical-grade vs. research-chemical sourcing
APA & SSRP Institute verified member
Dr. Amy Seinfeld, D.O.

Medical Authority

Dr. Amy Seinfeld, D.O.

Formulation Authority · Ginspire Health LLC · Boca Raton, FL

"Every product we offer is something I stand behind clinically. Our formulations are designed for real outcomes — not marketing claims."

How We Operate

Built Around Clinical Standards, Not Marketing
Every formulation is reviewed by Dr. Amy Seinfeld before it reaches a customer — not handed off to a contract manufacturer with no clinical input.
Pharmaceutical-Grade, Not Research-Chemical
Sourced and manufactured to 503A compounding pharmacy standards. Every batch is third-party tested for purity, potency, and safety.
We Treat You Like a Patient, Not an Order Number
Our team understands what you're taking and why. If something goes wrong with your order, we fix it. No automated runaround.
DSIP vs prescription sleep aids

The Comparison

DSIP vs. Prescription Sleep Aids

Prescription sleep medications — benzodiazepines and "Z-drugs" like zolpidem — work by suppressing your central nervous system. They can knock you out, but they also blunt your natural sleep architecture, and they carry real trade-offs: next-day impairment, tolerance that builds over time, dependency, and rebound insomnia when you stop.

DSIP takes the opposite approach. Rather than forcing sleep through sedation, it works with your body — lowering cortisol and supporting the transition into the deep sleep stages you're already capable of. No sedation hangover, no habit formation, no rebound. That's why it appeals to people who want real rest without the baggage of a prescription sedative.

Is DSIP a sedative?
No. Sedatives suppress your nervous system to force sleep. DSIP supports your body's own ability to reach deep sleep, without sedation.
Is DSIP habit-forming like sleeping pills?
DSIP is non-habit-forming with no known rebound insomnia, and is designed for consistent nightly use without dependency.
Can DSIP replace my prescription?
That's a decision for you and your physician. Many people use DSIP as a natural alternative — but never stop a prescribed medication without medical guidance.

* These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before changing any prescribed medication.

Important — read before opening

Before You Use Your Nasal Spray

Your spray ships in two parts. Take 60 seconds to assemble before first use.

Spray bottle and pump assembly
1
Check Your Package Contents
Your spray ships in two parts: the bottle and the pump mechanism. Both are inside the box. Do not discard anything until you have located both pieces.
Do not throw away any packaging until your spray is fully assembled.
2
Remove the Protective Cap From the Pump
Locate the pump mechanism inside the box. Remove the small protective cap covering the nozzle tip and set it aside — you'll reuse it to seal the spray between doses.
3
Attach the Pump to the Bottle
Insert the pump stem into the top of the bottle and press down firmly until it clicks into place and sits flush with the bottle neck. It should feel secure and not wobble.
4
Prime Before First Use
Hold the bottle upright and depress the pump 3–5 times until a fine mist appears. This purges air from the stem. Your spray is now ready.
Prime into a tissue — not toward yourself or others.
5
Replace the Cap and Refrigerate
After each use, replace the protective cap over the nozzle. Refrigeration is required. Store upright, away from strong odors. Do not freeze.
Recommended Usage
Use as directed. Most protocols call for 1 spray per nostril at night, 30–60 minutes before bed. Do not exceed 4 sprays per 24 hours.
If anything appears to be missing from your order, do not discard the packaging. Contact support@drseinfeld.com and we'll make it right.

Verified & Trusted

Memberships & Affiliations

We hold ourselves to the standards set by the bodies advancing peptide science — so you can have full confidence in every product you receive.

Verified Membership

American Peptide Association

The leading industry body advancing the science, safety, and standards of peptide research. Our membership reflects our commitment to purity, transparency, and responsible sourcing.

Verified Membership

Seeds Scientific Research & Performance Institute

A physician-led institute advancing the clinical standards of peptide therapy and cellular medicine. Our membership reflects our commitment to evidence-based, physician-guided care.

SQF Certified
FDA Registered
Third-Party Tested
503A Compounded
Made in USA
SQF CertifiedFDA RegisteredThird Party TestedScience-BackedManufactured in USAClean IngredientsGluten FreeNon-GMO

Statements on this website have not been evaluated by the Food and Drug Administration (FDA). Products offered are intended for general wellness purposes only and are not intended to diagnose, treat, cure, or prevent any disease. Products are provided for personal use as part of a wellness-focused lifestyle. Please follow all usage instructions and consult a qualified healthcare professional if you have questions regarding individual use.